Mixing alcohol and medication is never a good idea. It has not been proven that drinking alcohol can worsen the symptoms of IBD. Drinking alcohol can have significant adverse effects on your gastrointestinal tract as well as the rest of your body.
Evidence shows that the lining of the gastrointestinal (GI) tract gets irritated after drinking alcohol. The results of this irritation can include nausea, vomiting, diarrhea, and bleeding.
Alcohol can damage the liver by destroying or altering its cells and may even worsen an existing liver condition. Chronic liver disease is a serious complication of IBD that affects from 5% to 15% of people with IBD.