Inflammatory bowel disease (IBD) is a group of intestinal disorders characterized by chronic relapsing inflammation of the digestive tract. The two most common subtypes are Crohn’s disease Crohn’s disease(CD) and ulcerative colitis (UC). Although CD and UC have overlapping characteristics, the clinical presentations, genetic associations, gene expression patterns, and immune responses differ.
Crohn’s Disease is a type of IBD that can affect any part of the gastrointestinal (GI) tract from the mouth to the anus. It most commonly affects the end of the small intestine (the ileum) and the beginning of the large intestine (the colon).
Ulcerative Colitis (UC) is a type of IBD that affects a part of the gut called the large intestine, or the colon, as well as the rectum. It causes a continuous inflammation, which usually begins at the anus. The ulcers and inflammation associated with UC can cause bloody diarrhea often with rectal urgency, stomach pain, diarrhea, weight loss, as well as other symptoms.
Indeterminate Colitis (IC) is a type of IBD that may be diagnosed if your symptoms don’t entirely match either Crohn’s Disease or Ulcerative Colitis. IC causes ulcers and inflammation in your gastrointestinal (GI) tract causing pain and frequent bathroom visits.
IC is typically treated in a similar manner to ulcerative colitis. There are several treatment options available including drugs, surgery, and careful attention to nutrition and diet. Your doctor will help determine which treatment options will work best for you. These treatments depend on how bad your pain is and what other symptoms you may have.
Symptoms vary from abdominal pain and typically non-bloody diarrhea to more severe forms involving penetration through the bowel and formation of fistulas, strictures, and abscesses.